Thermal analysis applications with cosmetics, pharmaceuticals and food

Many pharmaceutical drugs contain ingredients that are highly sensitive to heat and can rapidly lose their effectiveness when exposed to elevated temperatures. This is particularly true for emulsions, which can change in consistency or separate into their constituents when subjected to even moderate temperature variations. Moreover, fats within these emulsions can spoil, rendering the drug unusable.

A considerable number of medications must be stored in refrigerated conditions to prevent rapid degradation. In Germany alone, there are over 2,000 refrigerated or cold chain products, including specialized vaccines, asthma sprays, and insulins, which must not exceed a temperature of 8°C for an extended period. Beyond pharmaceuticals for medical use, there are numerous cosmetic products like lotions that are also heat-sensitive, necessitating specialized protection during storage and transport.

One effective approach to mitigate the impact of thermal influences on drugs is through suitable packaging. However, identifying the appropriate packaging solutions requires a deep understanding of the characteristics of the ingredients used.

In the field of pharmacology, analytical techniques such as thermal analysis and calorimetry play a vital role, primarily for characterizing the main active ingredients and determining the pharmaceutical dosage form. Instruments provided by LINSEIS are well-suited for this purpose due to their exceptional sensitivity, enabling the detection of even the slightest thermal reactions with minimal sample quantities. This makes LINSEIS instruments invaluable tools in the delicate realm of pharmaceutical research and development.


Chip-DSC 10 – foods on DSC – chocolate
THB 100 – Milk powder – Thermal conductivity
Chip-DSC 10 – DSC of pharmaceuticals – Glass point sorbitol
Chip-DSC 100 – Xerogel nanoparticles
Chip-DSC 10 – food industries (lactose) – characterization of glasstransitions
Chip-DSC 10 – food testing – butter and maragarine
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