In a specific instance, sorbitol, a synthetic C-6 sugar-alcohol commonly utilized as a sugar substitute in sweets, diet products, and as a carrier substance in pharmaceuticals, underwent investigation using Chip-DSC 10 with a quench cooler.

The objective of the measurement was to illustrate the influence of humidity on the product’s structure. Two samples were analyzed: one with 5.4% water content and another water-free sample. The measurement spanned from -70°C to 50°C. The results revealed a notable difference in the glass transition temperature of water-free sorbitol (depicted by the blue curve) at -3.9°C, as opposed to the sample containing 5.4% water (represented by the red curve) with a lowered glass transition temperature of -28.7°C. This shift in temperature may also impact the crystal structure of the solid and holds significance for the product’s storage conditions.